Natriuretic Peptide Receptor C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97777

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all NPRC/NPR3 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-HRELREDSIRSHFS corresponding to C-Terminus according to NP_000899.1.

Specificity

The immunizing peptide represents the cytoplasmic part of the protein.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Natriuretic Peptide Receptor C Antibody

Western Blot: Natriuretic Peptide Receptor C Antibody [NBP1-97777]

Western Blot: Natriuretic Peptide Receptor C Antibody [NBP1-97777]

Western Blot: Natriuretic Peptide Receptor C Antibody [NBP1-97777] - (1ug/ml) Analysis of Human Placenta lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-97777]

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-97777]

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-97777] - (10ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-97777]

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-97777]

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-97777] - (2ug/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.
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Applications for Natriuretic Peptide Receptor C Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

2-4 ug/ml

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
Western blot: Approx 52kDa band observed in Human Placenta lysates (calculated MW of 59.8kDa according to NP_000899.1).
IHC: In paraffin embedded Human Kidney shows staining of brush borders in select PCT. Recommended concentration, 2-4ug/ml.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NPRC/NPR3

The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM]

Long Name

Natriuretic Peptide Receptor C

Alternate Names

ANP-C, ANPR-C, C5orf23, GUCY2B, lgj, NPR-C, NPR3, stri

Entrez Gene IDs

4883 (Human); 18162 (Mouse); 25339 (Rat)

Gene Symbol

NPR3

UniProt

NP_000899.1 (Human)

Additional NPRC/NPR3 Products

Product Documents for Natriuretic Peptide Receptor C Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Natriuretic Peptide Receptor C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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