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NEIL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-881

Novus Biologicals, part of Bio-Techne
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NB300-881

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

This NEIL1 Antibody was developed against a peptide with sequence C-DIPSLEPEGTSAS corresponding to C-Terminus according to NP_078884.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NEIL1 Antibody

Immunohistochemistry-Paraffin: NEIL1 Antibody [NB300-881]

Immunohistochemistry-Paraffin: NEIL1 Antibody [NB300-881]

Immunohistochemistry-Paraffin: NEIL1 Antibody [NB300-881] - Analysis of NEIL1 in paraffin embedded Human Placenta using this antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Human placenta shows strong staining of cytoplasm in syncytiotrophoblasts.

Applications for NEIL1 Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/mL

Immunohistochemistry-Paraffin

5 - 10 ug/mL

Peptide ELISA

Detection limit 1:16000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NEIL1

NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM]

Alternate Names

DNA-(apurinic or apyrimidinic site) lyase Neil1, EC 3.2.2.-, EC 4.2.99.18, endonuclease 8-like 1, endonuclease VIII, Endonuclease VIII-like 1, FLJ22402, FPG1DNA glycosylase/AP lyase Neil1, hFPG1, NEH1, nei endonuclease VIII-like 1 (E. coli), Nei homolog 1, NEI1, Nei-like protein 1

Entrez Gene IDs

79661 (Human)

Gene Symbol

NEIL1

Additional NEIL1 Products

Product Documents for NEIL1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NEIL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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