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NEK2 Antibody (JE37-74)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-32642

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-32642

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # JE37-74

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide within Human NEK2 aa 1-50 / 445. (Uniprot: P51955)

Localization

Nucleus, nucleolus, Cytoplasm.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NEK2 Antibody (JE37-74)

NEK2 Antibody (JE37-74)

Western Blot: NEK2 Antibody (JE37-74) [NBP3-32642]

Western Blot: NEK2 Antibody (JE37-74) [NBP3-32642] - Western blot analysis of NEK2 on different lysates with Rabbit anti-NEK2 antibody (NBP3-32642) at 1/1,000 dilution.

Lane 1: A549 cell lysate
Lane 2: Hela cell lysate

Lysates/proteins at 10 ug/Lane.

Predicted band size: 52 kDa
Observed band size: 52 kDa

Exposure time: 2 minutes;

10% SDS-PAGE gel.

Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-32642) at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:200,000 dilution was used for 1 hour at room temperature.

Applications for NEK2 Antibody (JE37-74)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

1*TBS (pH7.4), 0.05% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NEK2

Protein kinase that is involved in mitotic regulation. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not

Long Name

NIMA [Never In Mitosis Gene A]-related Kinase 2

Alternate Names

HsPK21, NLK1

Gene Symbol

NEK2

Additional NEK2 Products

Product Documents for NEK2 Antibody (JE37-74)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NEK2 Antibody (JE37-74)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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