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Neprilysin/CD10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49050

Novus Biologicals, part of Bio-Techne
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NBP2-49050
NBP2-49050-25ul

Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Neprilysin/CD10 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Neprilysin/CD10 Antibody

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody [NBP2-49050]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody [NBP2-49050]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody [NBP2-49050] - Staining of human prostate.
Immunohistochemistry: Neprilysin/CD10 Antibody [NBP2-49050]

Immunohistochemistry: Neprilysin/CD10 Antibody [NBP2-49050]

Immunohistochemistry: Neprilysin/CD10 Antibody [NBP2-49050] - Staining of human duodenum shows strong positivity brush border.
Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody [NBP2-49050]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody [NBP2-49050]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody [NBP2-49050] - Staining of human cerebral cortex shows low expression as expected.

Applications for Neprilysin/CD10 Antibody

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neprilysin/CD10

CD10, also known as the Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Alternate Names

CALLA, CD10, Enkephalinase, Leu-19, MME, Neutral Endopeptidase 24.11, NKH1

Gene Symbol

MME

Additional Neprilysin/CD10 Products

Product Documents for Neprilysin/CD10 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Neprilysin/CD10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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