Neurocan Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84368

Novus Biologicals, part of Bio-Techne
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NBP1-84368
NBP1-84368-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Neurocan Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TDASERGLHMQKLGSGSVQAALAELVALPCLFTLQPRPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVVRVAKSWQGR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Neurocan Antibody

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368]

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368]

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368] - Staining in human cerebral cortex and pancreas tissues using anti-NCAN antibody. Corresponding NCAN RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368]

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368]

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368]

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368]

Immunohistochemistry-Paraffin: Neurocan Antibody [NBP1-84368] - Staining of human cerebral cortex shows high expression.

Applications for Neurocan Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neurocan

Neurocan is the major soluble chondroitin sulfate proteoglycan in the brain. It is thought to play a functional role in axonal growth and guidance and in the establishment of specific neural pathways during embryonic brain development. Neurocan expression in the brain is developmentally regulated. Early on the major form of Neurocan consists of a 245kD core protein with approximately two chondroitin sulfate glycosoaminoglycan chains of 22kD each. Later Neurocan comprises a 180kD core protein Both forms of Neurocan contain only chondroitin 4-sulfate glycosoaminoglycan chains. By virtue of their high expression at sites of neural damage and trauma, chondroitin sulfate proteoglycans, including Neurocan, are thought to inhibit successful nerve regeneration.

Alternate Names

CSPG3, NCAN, NEUR

Gene Symbol

NCAN

Additional Neurocan Products

Product Documents for Neurocan Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neurocan Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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