Neuroglycan C/CSPG5 Antibody (5C11)

Novus Biologicals, part of Bio-Techne | Catalog # H00010675-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 5C11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Neuroglycan C/CSPG5 Antibodies »

Product Specifications

Immunogen

CSPG5 (NP_006565, 445 a.a. ~ 539 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT

Reactivity Notes

Human. Other species not tested.

Localization

Endoplasmic reticulum, Golgi Apparatus and Plasma membrane

Specificity

CSPG5 - chondroitin sulfate proteoglycan 5 (neuroglycan C)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Neuroglycan C/CSPG5 Antibody (5C11)

Sandwich ELISA: Neuroglycan C/CSPG5 Antibody (5C11) [H00010675-M01] - Detection limit for recombinant GST tagged CSPG5 is approximately 1ng/ml as a capture antibody.

Applications for Neuroglycan C/CSPG5 Antibody (5C11)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Neuroglycan C/CSPG5

Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system.

Alternate Names

CALEB, CSPG5, NGC

Entrez Gene IDs

10675 (Human)

Gene Symbol

CSPG5

OMIM

606775 (Human)

UniProt

NP_006565 (Human)

Additional Neuroglycan C/CSPG5 Products

Product Documents for Neuroglycan C/CSPG5 Antibody (5C11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Neuroglycan C/CSPG5 Antibody (5C11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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