Neuroglycan C/CSPG5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49669

Novus Biologicals, part of Bio-Techne
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NBP2-49669
NBP2-49669-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Neuroglycan C/CSPG5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EEDDKDAVGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSE

Reactivity Notes

Mouse (82%), Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Neuroglycan C/CSPG5 Antibody

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669]

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669]

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669] - Staining in human cerebral cortex and pancreas tissues using anti-CSPG5 antibody. Corresponding CSPG5 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669]

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669]

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669]

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669]

Immunohistochemistry-Paraffin: Neuroglycan C/CSPG5 Antibody [NBP2-49669] - Staining of human cerebral cortex shows high expression.

Applications for Neuroglycan C/CSPG5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neuroglycan C/CSPG5

Many cellular activities depend on the interaction of cells with the surrounding extracellular matrix (ECM). Most cells, in intact tissue and in culture, are attached to an ECM. Epithelial cells are associated with the basement membrane; fibroblastic cells are usually embedded in a pericellular mesh of fibrils, and tissue culture cells usually grow on a substrate which is covered by various ECM components. Studies have indicated that the matrix or its various isolated components provide not only adhesive surfaces for cells to grow on but also have effects on the rate of cell growth, mobility, morphogenesis and differentiation. Within the ECM several glycoproteins and proteoglycans have been identified. It has been proposed that the different constituents interact with each other in a rather complex fashion. The poor antigenicity of proteoglycans especially their glycoaminoglycan (GAG) moieties make it difficult to localize these molecules in tissue and cell culture. Monoclonal Anti-Chondroitin Sulfate can be used to study chondroitin sulfate proteoglycan (CSPG) distribution and its relationships to specific cell-substrate contacts.

Alternate Names

CALEB, CSPG5, NGC

Gene Symbol

CSPG5

Additional Neuroglycan C/CSPG5 Products

Product Documents for Neuroglycan C/CSPG5 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Neuroglycan C/CSPG5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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