Neurturin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-68153

Novus Biologicals, part of Bio-Techne
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NB100-68153
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Neurturin Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-DVHSRYHTLQELSARE corresponding to C-Terminus according to Uniprot Mouse NP_032764.1.

Epitope

DVHSRYHTLQELSARE

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Neurturin Antibody

Western Blot: Neurturin Antibody [NB100-68153]

Western Blot: Neurturin Antibody [NB100-68153]

Western Blot: Neurturin Antibody [NB100-68153] - Analysis of Neurturin (mouse) antibody using this antibody at 0.1 ug/ml in mouse brain lysate.

Applications for Neurturin Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 22-23 kDa band observed in mouse brain and rat brain lysates (calculated MW of 22.4 kDa band according to mouse NP_032764.1). An additional very strong band of unknown identity was also consistently observed at 50 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Neurturin

TGF-beta with neurturin and persephin are required for the induction of dopaminergic neurons, whereas GDNF is required for regulating and/or maintaining a differentiated neuronal phenotype. Neurturin-mediated Ret signaling is critical to normal retinal development and function. This study revealed the complexity of postnatal maturation of urogenital innervation, with each organ showing a distinct chronology of innervation and different requirement for neurturin. Transduction-function role for GFR alpha2/neurturin signaling in a specific class of sensory neurons.

Alternate Names

NRTN, NTN

Entrez Gene IDs

18188 (Mouse); 84423 (Rat)

Gene Symbol

NRTN

UniProt

NP_032764.1 (Mouse)

Additional Neurturin Products

Product Documents for Neurturin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neurturin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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