NFkB2/NFkB p100 Antibody (CL8266)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88914

Novus Biologicals, part of Bio-Techne
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NBP2-88914
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL8266

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NFkB2 Antibodies »

Product Summary for NFkB2/NFkB p100 Antibody (CL8266)

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids: LKRKRGGDVSDSKQFTYYP

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for NFkB2/NFkB p100 Antibody (CL8266)

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914]

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914]

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914] - Analysis in human tonsil and skeletal muscle tissues using NBP2-88914 antibody. Corresponding NFKB2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914]

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914]

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914] - Staining of human tonsil shows strong nuclear positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914]

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914]

Immunohistochemistry-Paraffin: NFkB2/NFkB p100 Antibody (CL8266) [NBP2-88914] - Staining of human Fallopian tube shows strong nuclear positivity in glandular cells.
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Applications for NFkB2/NFkB p100 Antibody (CL8266)

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NFkB2

NFkB1 (NFkB p50) and NFkB2 (NFkB p52) are class I members of the Rel/NFkB family of transcription factors that also includes RelA, c-Rel and RelB. Rel/NFkB members regulate expression of genes that participate in immune, apoptotic and oncogenic processes. Class I members lack a C-terminal transcriptional activation segment found in class II members, but contain an RHD (Rel homology domain) that mediates DNA binding, nuclear localization and dimerization. NFkB1 and NFkB2 105 and 100 kDa precursors are proteolytically cleaved to 50 and 52 kDa active subunits, respectively. NFkB is predominantly localized in the cytoplasm as a complex with inhibitory IkB proteins and is released and translocated to the nucleus after phosphorylation of IkB.

Long Name

Nuclear Factor Kappa-B, Subunit 2

Alternate Names

LYT10, NF-kB2

Gene Symbol

NFKB2

Additional NFkB2 Products

Product Documents for NFkB2/NFkB p100 Antibody (CL8266)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NFkB2/NFkB p100 Antibody (CL8266)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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