NFKBIL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-70344

Novus Biologicals, part of Bio-Techne
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NBP1-70344
NBP1-70344SS
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Key Product Details

Species Reactivity

Human, Amphibian, Bovine, Canine, Chimpanzee, Equine, Primate

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all NFKBIL1 Antibodies »

Product Specifications

Immunogen

Amino acids RRYLRVQQVRWHPDRFLQR (331-349) of human NFKBIL1 were used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in new world monkey, panda, mouse lemur, chimpanzee, orangutan, rhesus monkey, wild pig, 95% homologous in horse, rat, mouse, 89% homologous in frog, opossum, sea anemone and 74% homologous in platypus and carolina anole. Reacts with Frog.

Specificity

There are multiple isoforms of this protoein. The amino acid sequenced used as immunogen is provided to help researchers determine suitability of this antibody for their testing.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NFKBIL1 Antibody

Western Blot: NFKBIL1 Antibody [NBP1-70344]

Western Blot: NFKBIL1 Antibody [NBP1-70344]

Western Blot: NFKBIL1 Antibody [NBP1-70344] - analysis of NFKBIL1. Lanes 1 and 2 show HeLa cell lysate probed with pre-immune sera (1:5000) and NFKBIL1 polyclonal antibody (3 ug/ml), respectively.

Applications for NFKBIL1 Antibody

Application
Recommended Usage

Western Blot

2-4 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NFKBIL1

NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins. NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers and co-localized in CD68+ and CD3+, but not Factor VIII+ cells. It is reported that defects in NFKBIL1 expression causes of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and affects the joints. Rheumatoid arthritis (RA) is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.

Alternate Names

IkappaBL, I-kappa-B-like protein, IKBLikappaBL, Inhibitor of kappa B-like protein, LST1, NF-kappa-B inhibitor-like protein 1, nuclear factor of kappa light polypeptide gene enhancer in B-cellsinhibitor-like 1NFKBIL

Gene Symbol

NFKBIL1

UniProt

NP_004998.3 (Human)

Additional NFKBIL1 Products

Product Documents for NFKBIL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NFKBIL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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