NG2/MCSP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-21361

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-21361
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all NG2/MCSP Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 575 and 625 of human melanoma-associated chondroitin sulfate proteoglycan (chondroitin sulfate proteoglycan 4 ) using the numbering given in entry NP_001888.2 (GeneID 1464).

Reactivity Notes

Porcine reactivity reported from a verified customer review.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The porcine reactivity was reported by an anonymous customer.

Scientific Data Images for NG2/MCSP Antibody

Western Blot: NG2/MCSP Antibody [NBP1-21361]

Western Blot: NG2/MCSP Antibody [NBP1-21361]

Western Blot: NG2/MCSP Antibody [NBP1-21361] - NG2 Antibody [NBP1-21361] - Whole cell lysate from HeLa cells. MCSP was also immunoprecipitated by rabbit anti-MCSP antibody NBP1-21362.
Immunocytochemistry/ Immunofluorescence: NG2/MCSP Antibody [NBP1-21361]

Immunocytochemistry/ Immunofluorescence: NG2/MCSP Antibody [NBP1-21361]

Immunocytochemistry/Immunofluorescence: NG2/MCSP Antibody [NBP1-21361] - NG2 Antibody [NBP1-21361] - Primary cultured trabecular meshwork cells from porcine eye. Left non stretched TM cells; Right 24 hours stretched TM cells. Annonymous Customer Reported Findings.

Applications for NG2/MCSP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Validated from a verified customer review

Immunoprecipitation

5-10 ug/mg lysate

Western Blot

1:2000-1:10000

Reviewed Applications

Read 1 review rated 5 using NBP1-21361 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: NG2/MCSP

Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.

Long Name

Chondroitin Sulfate Proteoglycan NG2/Melanoma Associated Chondroitin Sulfate Proteoglycan

Alternate Names

AN2, CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG

Entrez Gene IDs

1464 (Human)

Gene Symbol

CSPG4

UniProt

Q6UVK1

Additional NG2/MCSP Products

Product Documents for NG2/MCSP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NG2/MCSP Antibody

The porcine reactivity was reported by an anonymous customer.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.