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NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19726

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19726-100ul
NBP3-19726-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-1C7

Concentration

0.3 mg/ml

Product Summary for NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7)

Immunogen

A synthetic peptide of human NGFI-B alpha/Nur77/NR4A1 (Uniprot # P22736)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7)

Western Blot: NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7) [NBP3-19726]

Western Blot: NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7) [NBP3-19726]

Western Blot: NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7) [NBP3-19726] - Western blot detection of NGFI-B alpha/Nur77/NR4A1 in Rat Brain lysates using NBP3-19726 (1:500 diluted). Predicted band size: 65kDa. Observed band size: 65kDa.

Applications for NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7)

Application
Recommended Usage

Western Blot

1/1000-1/5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NGFI-B alpha/Nur77/NR4A1

Nak1 is a member of the steroid/thyroid hormone receptor superfamily. The gene for Nak-1 is induced rapidly by androgens/growth factors and may have functions related to cell proliferation, differentiation and apoptosis (1). Liu et al (2) have demonstrated that mouse nur77 is necessary for induced apoptosis in T-cell hybridomas and can also be induced during early mitogenesis. Nak1 is a phosphoprotein and its size ranges from 67 kD to 88 kD, depending on post-translational modifications.

Long Name

Nerve Growth Factor-induced Protein I-B alpha/Nuclear Receptor Subfamily 4, Group A, Member 1

Alternate Names

HMR, NAK1, NGFIB alpha, NR4A1, Nur77, TR3

Gene Symbol

NR4A1

Additional NGFI-B alpha/Nur77/NR4A1 Products

Product Documents for NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NGFI-B alpha/Nur77/NR4A1 Antibody (S02-1C7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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