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Nicotinic Acetylcholine Receptor beta Antibody (4G4)

Novus Biologicals, part of Bio-Techne | Catalog # H00001140-M01

Novus Biologicals, part of Bio-Techne
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H00001140-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 4G4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

CHRNB1 (NP_000738, 24 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALD

Specificity

CHRNB1 - cholinergic receptor, nicotinic, beta 1 (muscle)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Nicotinic Acetylcholine Receptor beta Antibody (4G4)

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody (4G4) [H00001140-M01]

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody (4G4) [H00001140-M01]

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody (4G4) [H00001140-M01] - Detection against Immunogen (37.29 KDa) .

Applications for Nicotinic Acetylcholine Receptor beta Antibody (4G4)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Nicotinic Acetylcholine R beta 1/CHRNB1

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Long Name

Nicotinic Acetylcholine Receptor beta 1

Alternate Names

ACHRB, CHRNB1, CMS1D, CMS2C, nAChRB1

Entrez Gene IDs

1140 (Human)

Gene Symbol

CHRNB1

OMIM

100710 (Human)

UniProt

Additional Nicotinic Acetylcholine R beta 1/CHRNB1 Products

Product Documents for Nicotinic Acetylcholine Receptor beta Antibody (4G4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Nicotinic Acetylcholine Receptor beta Antibody (4G4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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