Nicotinic Acetylcholine Receptor beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-20900

Novus Biologicals, part of Bio-Techne
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NBP1-20900
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Nicotinic Acetylcholine R beta 1/CHRNB1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QEQEDHDALKED corresponding to internal region according to NP_000738.2.

Epitope

C terminus

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Nicotinic Acetylcholine Receptor beta Antibody

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody [NBP1-20900]

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody [NBP1-20900]

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody [NBP1-20900] - Analysis of Nicotinic Acetylcholine Receptor beta in human cerebellum lysate (35ug protein in RIPA buffer) using NBP1-20900 at 1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Nicotinic Acetylcholine Receptor beta Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:1000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 55 kDa band observed in human brain (cerebellum, hippocampus, frontal cortex) lysates (calculated MW of 56.7 kDa band according to NP_000738.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Nicotinic Acetylcholine R beta 1/CHRNB1

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Long Name

Nicotinic Acetylcholine Receptor beta 1

Alternate Names

ACHRB, CHRNB1, CMS1D, CMS2C, nAChRB1

Entrez Gene IDs

1140 (Human); 24261 (Rat)

Gene Symbol

CHRNB1

UniProt

NP_000738.2 (Human)

Additional Nicotinic Acetylcholine R beta 1/CHRNB1 Products

Product Documents for Nicotinic Acetylcholine Receptor beta Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Nicotinic Acetylcholine Receptor beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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