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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NIPSNAP. The immunogen is located within the last 50 amino acids of NIPSNAP. Amino Acid Squence: SREETRNAAWRKRGWDEN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NIPSNAP1 Antibody - BSA Free

Western Blot: NIPSNAP1 AntibodyBSA Free [NBP1-76887]

Western Blot: NIPSNAP1 AntibodyBSA Free [NBP1-76887]

Western Blot: NIPSNAP1 Antibody [NBP1-76887] - Human brain tissue lysate with NIPSNAP antibody at (A) 0.5 and (B) 1 ug/ml.
Immunohistochemistry-Paraffin: NIPSNAP1 Antibody - BSA Free [NBP1-76887]

Immunohistochemistry-Paraffin: NIPSNAP1 Antibody - BSA Free [NBP1-76887]

Immunohistochemistry-Paraffin: NIPSNAP1 Antibody [NBP1-76887] - Human brain tissue using Nipsnap1 antibody at 2.5 ug/ml.

Immunocytochemistry/Immunofluorescence: NIPSNAP1 Antibody [NBP1-76887] -

Immunocytochemistry/Immunofluorescence: NIPSNAP1 Antibody [NBP1-76887] - Human Brain cells with NIPSNAP antibody at 20 ug/mL.

Applications for NIPSNAP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NIPSNAP1

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.

Alternate Names

nipsnap homolog 1 (C. elegans), NIPSNAP, C. elegans, homolog 1,4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1, NipSnap1, protein NipSnap homolog 1

Gene Symbol

NIPSNAP1

Additional NIPSNAP1 Products

Product Documents for NIPSNAP1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NIPSNAP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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