NK1R Antibody (1E5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15240

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15240
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1E5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NK1R Antibodies »

Product Summary for NK1R Antibody (1E5)

Immunogen

A synthesized peptide derived from human NK1R. UniProt ID (P25103).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NK1R Antibody (1E5)

Western Blot: NK1R Antibody (1E5) [NBP3-15240]

Western Blot: NK1R Antibody (1E5) [NBP3-15240]

Western Blot: NK1R Antibody (1E5) [NBP3-15240] - Positive WB detected in: THP-1 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, Ntera-2 whole cell lysate, Mouse Brain whole cell lysate. All lanes: NK1R antibody at 1:1000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 47, 36 KDa. Observed band size: 50 KDa.

Applications for NK1R Antibody (1E5)

Application
Recommended Usage

Western Blot

1:500-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: NK1R

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Long Name

Neurokinin-1 Receptor

Alternate Names

SPR, TAC1R, TACR1

Gene Symbol

TACR1

Additional NK1R Products

Product Documents for NK1R Antibody (1E5)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NK1R Antibody (1E5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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