NKCC1/SLC12A2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56180

Novus Biologicals, part of Bio-Techne
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NBP2-56180
NBP2-56180-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NKCC1/SLC12A2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NKCC1/SLC12A2 Antibody

Immunocytochemistry/ Immunofluorescence: NKCC1/SLC12A2 Antibody [NBP2-56180]

Immunocytochemistry/ Immunofluorescence: NKCC1/SLC12A2 Antibody [NBP2-56180]

Immunocytochemistry/Immunofluorescence: NKCC1/SLC12A2 Antibody [NBP2-56180] - Staining of human cell line U-2 OS shows localization to plasma membrane & vesicles. Antibody staining is shown in green.

Applications for NKCC1/SLC12A2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NKCC1/SLC12A2

Belonging to the SLC12A transporter family, NKCC1 is located on the basolateral membrane of secretory epithelia. Playing an important role in ionic balance and cell volume, NKCC1 is an electrically silent transporter system that mediates sodium, potassium and chloride transport and reabsorption. NKCC1 has interaction with OXSR1, STK39, MAPK14, UBC and RANBP2. Diseases associated with NKCC1 include hearing loss, growth failure, bleeding, torticollis and small intestinal prolapse and Bartter disease.

Long Name

Sodium/Potassium/Chloride Transporter NKCC1

Alternate Names

BSC2, SLC12A2

Gene Symbol

SLC12A2

Additional NKCC1/SLC12A2 Products

Product Documents for NKCC1/SLC12A2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NKCC1/SLC12A2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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