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NKX6.1 Antibody (NKX61/2561)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79737

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2c Kappa Clone # NKX61/2561

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant full-length human NKX6.1 protein (Uniprot: P78426)

Localization

Nuclear

Marker

Marker for Pancreatic and Duodenal Neuroendocrine Tumors

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2c Kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml.(NBP2-79872)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for NKX6.1 Antibody (NKX61/2561)

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) [NBP2-79737]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) [NBP2-79737]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) [NBP2-79737] - Formalin-fixed, paraffin-embedded human Pancreas stained with NKX6.1 Antibody (NKX61/2561).
Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) [NBP2-79737]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) [NBP2-79737]

Immunohistochemistry-Paraffin: NKX6.1 Antibody (NKX61/2561) [NBP2-79737] - Formalin-fixed, paraffin-embedded human Pancreas stained with NKX6.1 Antibody (NKX61/2561).
Protein Array: NKX6.1 Antibody (NKX61/2561) [NBP2-79737]

Protein Array: NKX6.1 Antibody (NKX61/2561) [NBP2-79737]

Protein Array: NKX6.1 Antibody (NKX61/2561) [NBP2-79737] - Analysis of Protein Array containing more than 19,000 full-length human proteins using NKX6.1 Antibody (NKX61/2561). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5.

Applications for NKX6.1 Antibody (NKX61/2561)

Application
Recommended Usage

Immunohistochemistry

1 - 2 ug/mL

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: NKX6.1

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM]

Long Name

NK6 Homeobox 1

Alternate Names

NKX6-1, NKX6A

Gene Symbol

NKX6-1

UniProt

Additional NKX6.1 Products

Product Documents for NKX6.1 Antibody (NKX61/2561)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NKX6.1 Antibody (NKX61/2561)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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