NKX6.1 Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49672F

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-49672AF350

Alexa Fluor 405

NBP1-49672AF405

Alexa Fluor 488

NBP1-49672AF488

Alexa Fluor 532

NBP1-49672AF532

Alexa Fluor 594

NBP1-49672AF594

Alexa Fluor 647

NBP1-49672AF647

Alexa Fluor 700

NBP1-49672AF700

Alexa Fluor 750

NBP1-49672AF750

Allophycocyanin

NBP1-49672APC

Biotin

NBP1-49672B

CoraFluor 1

NBP1-49672CL1

DyLight 350

NBP1-49672UV

DyLight 405

NBP1-49672V

DyLight 488

NBP1-49672G

DyLight 550

NBP1-49672R

DyLight 594

NBP1-49672DL594

DyLight 650

NBP1-49672C

DyLight 680

NBP1-49672FR

DyLight 755

NBP1-49672IR

HRP

NBP1-49672H

Janelia Fluor 525

NBP1-49672JF525

Janelia Fluor 549

NBP1-49672JF549

Janelia Fluor 585

NBP1-49672JF585

Janelia Fluor 635

NBP1-49672JF635

Janelia Fluor 646

NBP1-49672JF646

Janelia Fluor 669

NBP1-49672JF669

mFluor Violet 450 SE

NBP1-49672MFV450

mFluor Violet 500 SE

NBP1-49672MFV500

mFluor Violet 610 SE

NBP1-49672MFV610

PE

NBP1-49672PE

PerCP

NBP1-49672PCP

Forumulation

Catalog #

BSA Free

NBP1-49672

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, In vitro assay, Simple Western, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NKX6.1 Antibodies »

Product Specifications

Immunogen

A genomic peptide made to an internal region of the human Nkx6.1 protein (within residues 50-200). [Swiss-Prot P78426]

Reactivity Notes

Rat reactivity reported from a verified customer review.

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for NKX6.1 Antibody [FITC]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

In vitro assay

Optimal dilutions of this antibody should be experimentally determined.

Simple Western

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: NKX6.1

NKX6.1 (homeobox protein Nkx-6.1) is a transcription factor that binds to specific A/T-rich sequences in promoter regions of several genes and is known for its involvement in transcriptional regulation in islet beta cells via NKX6.1-insulin promoter binding mediated control of insulin gene. Together with NKX2-2 as well as IRX3, NKX6.1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. It belongs to neuronal progenitor factors class II proteins that are induced by SHH signals and is a member of the homeodomain family of transcription factors responsible for multiple organ systems development. The pancreatic development involves many such homeodomain proteins including Hb9, Pdx1, Pax4, Nkx2.2, and importantly on Nkx6.1 and mice deficient for Nkx6.1 display a dramatic reduction in beta-cell numbers in pancreas with near-normal development of other glandular cell types. Moreover, Nkx6.1 deficient mice have significant defects involving V2 interneuron and motor neuron specification in the ventral spinal cord, thereby emphasizing an important parallel in developmental pathways leading to beta-cells and neurons.

Long Name

NK6 Homeobox 1

Alternate Names

NKX6-1, NKX6A

Gene Symbol

NKX6-1

Additional NKX6.1 Products

Product Documents for NKX6.1 Antibody [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for NKX6.1 Antibody [FITC]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews