NLRP10/Pynod/NALP10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85557

Novus Biologicals, part of Bio-Techne
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NBP1-85557
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NLRP10/Pynod/NALP10 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NLRP10/Pynod/NALP10 Antibody

Western Blot: NLRP10/Pynod/NALP10 Antibody [NBP1-85557]

Western Blot: NLRP10/Pynod/NALP10 Antibody [NBP1-85557]

Western Blot: NLRP10/Pynod/NALP10 Antibody [NBP1-85557] - Analysis in control (vector only transfected HEK293T lysate) and NLRP10 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: NLRP10/Pynod/NALP10 Antibody [NBP1-85557]

Immunohistochemistry-Paraffin: NLRP10/Pynod/NALP10 Antibody [NBP1-85557]

Immunohistochemistry-Paraffin: NLRP10/Pynod/NALP10 Antibody [NBP1-85557] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: NLRP10/Pynod/NALP10 Antibody [NBP1-85557]

Immunohistochemistry-Paraffin: NLRP10/Pynod/NALP10 Antibody [NBP1-85557]

Immunohistochemistry-Paraffin: NLRP10/Pynod/NALP10 Antibody [NBP1-85557] - Staining of human cerebellum shows strong cytoplasmic positivity in cells in molecular layer.
View 1 more images

Applications for NLRP10/Pynod/NALP10 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NLRP10/Pynod/NALP10

Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs tothe NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innateimmune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates thepro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as amultifunctional negative regulator of inflammation and apoptosis. (provided by RefSeq)

Long Name

NLR Family, Pyrin Domain Containing 10

Alternate Names

NALP10, NOD8, PAN5, Pynod

Gene Symbol

NLRP10

Additional NLRP10/Pynod/NALP10 Products

Product Documents for NLRP10/Pynod/NALP10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NLRP10/Pynod/NALP10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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