NLRP10/Pynod/NALP10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76809

Novus Biologicals, part of Bio-Techne
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NBP2-76809
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Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all NLRP10/Pynod/NALP10 Antibodies »

Product Specifications

Immunogen

Peptide with sequence NDLEENSFKTLKFH-C, from the N Terminus of the protein sequence according to NP_780741.1.

Reactivity Notes

Expected to react with Rat.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NLRP10/Pynod/NALP10 Antibody

Flow Cytometry: NLRP10/Pynod/NALP10 Antibody [NBP2-76809]

Flow Cytometry: NLRP10/Pynod/NALP10 Antibody [NBP2-76809]

Flow Cytometry: NLRP10/Pynod/NALP10 Antibody [NBP2-76809] - Analysis of paraformaldehyde fixed NIH3T3 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
Immunofluorescence: NLRP10/Pynod/NALP10 Antibody [NBP2-76809]

Immunofluorescence: NLRP10/Pynod/NALP10 Antibody [NBP2-76809]

Immunofluorescence: NLRP10/Pynod/NALP10 Antibody [NBP2-76809] - Analysis of paraformaldehyde fixed NIH3T3 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/ml) followed by Alexa Fluor 488 secondary antibody (2 ug/ml), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/ml) followed by Alexa Fluor 488 secondary antibody (2 ug/ml).

Applications for NLRP10/Pynod/NALP10 Antibody

Application
Recommended Usage

Flow Cytometry

10 ug/ml

Peptide ELISA

Detection Limit 1:128000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline, pH7.3 with 0.5% bovine serum albumin.

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NLRP10/Pynod/NALP10

Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs tothe NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innateimmune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates thepro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as amultifunctional negative regulator of inflammation and apoptosis. (provided by RefSeq)

Long Name

NLR Family, Pyrin Domain Containing 10

Alternate Names

NALP10, NOD8, PAN5, Pynod

Entrez Gene IDs

244202 (Mouse); 293426 (Rat)

Gene Symbol

NLRP10

UniProt

NP_780741.1 (Human)

Additional NLRP10/Pynod/NALP10 Products

Product Documents for NLRP10/Pynod/NALP10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NLRP10/Pynod/NALP10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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