NLRP13 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32546

Novus Biologicals, part of Bio-Techne
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NBP2-32546
NBP2-32546-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NLRP13 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQED

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NLRP13 Antibody

Immunohistochemistry-Paraffin: NLRP13 Antibody [NBP2-32546]

Immunohistochemistry-Paraffin: NLRP13 Antibody [NBP2-32546]

Immunohistochemistry-Paraffin: NLRP13 Antibody [NBP2-32546] - Staining of human rectum shows strong cytoplasmic, membranous and nucleolar or nuclear positivity in glandular cells.

Applications for NLRP13 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NLRP13

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Alternate Names

CLR19.7, leucine rich repeat and pyrin domain containing 13, NACHT, leucine rich repeat and PYD containing 13, NACHT, LRR and PYD containing protein 13, NACHT, LRR and PYD domains-containing protein 13, NALP13, NLR family, pyrin domain containing 13, NOD14, nucleotide-binding oligomerization domain protein 14, PAN13

Gene Symbol

NLRP13

Additional NLRP13 Products

Product Documents for NLRP13 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NLRP13 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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