Key Product Details

Species Reactivity

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # T7

Format

Azide and BSA Free

Concentration

1.0 mg/ml

View all NMDAR2A Antibodies »

Product Specifications

Immunogen

Amino acid region 1099-1213 from human NMDAR2A produced as a GST fusion protein.

Specificity

Amino acid region 1099-1213 from human NMDAR2A produced as a GST fusion protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Relevant Entrez Gene Numbers: NM_000833.2

Applications for NMDAR2A Antibody (T7) - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2.5-5 ug/ml

Immunohistochemistry

2.5-5 ug/ml

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1-5 ug/ml
Application Notes
Immunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NMDAR2A

The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Alternate Names

GluN2A, glutamate receptor, ionotropic, N-methyl D-aspartate 2A, hNR2A, NMDA receptor subtype 2A, N-methyl D-aspartate receptor subtype 2A, N-methyl-D-aspartate receptor subunit 2A, subunit epsilon-1

Gene Symbol

GRIN2A

UniProt

Q12879 (Human)

Additional NMDAR2A Products

Product Documents for NMDAR2A Antibody (T7) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NMDAR2A Antibody (T7) - Azide and BSA Free

Relevant Entrez Gene Numbers: NM_000833.2

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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