NMDAR3B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52062

Novus Biologicals, part of Bio-Techne
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NBP1-52062
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all NMDAR3B Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EAPPHSGRPGSQ corresponding to C-Terminus according to NP_619635.1.

Epitope

C-EAPPHSGRPGSQ

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NMDAR3B Antibody

Western Blot: NMDAR3B Antibody [NBP1-52062]

Western Blot: NMDAR3B Antibody [NBP1-52062]

Western Blot: NMDAR3B Antibody [NBP1-52062] - NBP1-52062 (0.5ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for NMDAR3B Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.5 - 1.5 ug/ml
Application Notes
WB: Approx. 110 kDa band observed in human brain (cerebellum and cerebral cortex) lysates (calculated MW of 113 kDa band according to NP_619635.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NMDAR3B

The GRIN3B (NMDAR3B) gene encodes a 1,043 amino acid long, nearly 113 kDA glutamate receptor iontrophic, NMDA 3B that is a glycine controlled receptor that functions in glutamate-gated ion channels with reduced single-channel conductance, calcium, and voltage-sensitivity to magnesium. GRIN3B functions in glutamic acid signaling, the pathogenesis of ALS, the neuroactive ligand-receptor interaction, and the dopamine DARPP32 feedback onto cAMP pathway. This gene has been linked to HIV type 1, neuroblastoma, pain syndrome, opiod abuse, immunodeficiency, and alzheimer's disease.

Long Name

Glutamate receptor ionotropic, NMDA 3B

Alternate Names

GluN3B, GRIN3B, NR3B

Entrez Gene IDs

116444 (Human)

Gene Symbol

GRIN3B

UniProt

NP_619635.1 (Human)

Additional NMDAR3B Products

Product Documents for NMDAR3B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NMDAR3B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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