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non-muscle Myosin IIA [p Ser1943] Antibody (GT144)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13579

Novus Biologicals, part of Bio-Techne
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NBP3-13579

Key Product Details

Validated by

Knockout/Knockdown, Biological Validation

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # GT144

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for non-muscle Myosin IIA [p Ser1943] Antibody (GT144)

Immunogen

Carrier-protein conjugated synthetic peptide surrounding phospho Ser1943 of human non-muscle Myosin IIA. The exact sequence is proprietary.

Modification

p Ser1943

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

227 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Centrifuge briefly prior to opening.

Scientific Data Images for non-muscle Myosin IIA [p Ser1943] Antibody (GT144)

Western Blot: non-muscle Myosin IIA [p Ser1943] Antibody (GT144) [NBP3-13579] - Non-transfected (-) and transfected (+) HeLa whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with non-muscle Myosin IIA (phospho Ser1943) antibody [GT144] (NBP3-13579) diluted at 1:10000. The HRP-conjugated anti-mouset IgG antibody (NBP2-19382) was used to detect the primary antibody.
Immunocytochemistry/Immunofluorescence: non-muscle Myosin IIA [p Ser1943] Antibody (GT144) [NBP3-13579] - non-muscle Myosin IIA (phospho Ser1943) antibody [GT144] detects non-muscle Myosin IIA (phospho Ser1943) protein at cytoskeleton by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: non-muscle Myosin IIA (phospho Ser1943) protein stained by non-muscle Myosin IIA (phospho Ser1943) antibody [GT144] (NBP3-13579) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.
Immunohistochemistry-Paraffin: non-muscle Myosin IIA [p Ser1943] Antibody (GT144) [NBP3-13579] - Human mammary gland. non-muscle Myosin IIA (phospho Ser1943) antibody [144] (NBP3-13579) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

Applications for non-muscle Myosin IIA [p Ser1943] Antibody (GT144)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:5000-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Non-muscle Myosin IIA

The non-muscle Myosin IIA gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause

Long Name

Myosin-9

Alternate Names

MYH9, NMMHC II-a, NMMHC-A, NMMHC-IIA

Gene Symbol

MYH9

Additional Non-muscle Myosin IIA Products

Product Documents for non-muscle Myosin IIA [p Ser1943] Antibody (GT144)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for non-muscle Myosin IIA [p Ser1943] Antibody (GT144)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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