NPRB/NPR2 Antibody (2A6)

Novus Biologicals, part of Bio-Techne | Catalog # H00004882-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Sandwich ELISA Capture, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 2A6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NPRB/NPR2 Antibodies »

Product Specifications

Immunogen

NPR2 (NP_003986.2, 131 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPL

Specificity

NPR2 (2A6)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for NPRB/NPR2 Antibody (2A6)

Immunohistochemistry-Paraffin: NPRB/NPR2 Antibody (2A6) [H00004882-M01]

Immunohistochemistry-Paraffin: NPRB/NPR2 Antibody (2A6) [H00004882-M01]

Immunohistochemistry-Paraffin: NPRB/NPR2 Antibody (2A6) [H00004882-M01] - Analysis of monoclonal antibody to NPR2 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.
Sandwich ELISA Capture: NPRB/NPR2 Antibody (2A6) [H00004882-M01]

Sandwich ELISA Capture: NPRB/NPR2 Antibody (2A6) [H00004882-M01]

Sandwich ELISA Capture: NPRB/NPR2 Antibody (2A6) [H00004882-M01] - Detection limit for recombinant GST tagged NPRB/NPR2 is 1 ng/ml as a capture antibody.

Applications for NPRB/NPR2 Antibody (2A6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NPRB/NPR2

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Long Name

Natriuretic Peptide Receptor B

Alternate Names

AMDM, ANPb, ANPRB, ECDM, GC-B, GUC2B, NPR2, NPRBi, SNSK

Entrez Gene IDs

4882 (Human)

Gene Symbol

NPR2

OMIM

108961 (Human)

UniProt

CN841943 (Human)

Additional NPRB/NPR2 Products

Product Documents for NPRB/NPR2 Antibody (2A6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NPRB/NPR2 Antibody (2A6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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