NQO-2 Antibody (1E3) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-74033

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1E3

Format

BSA Free

Concentration

1 mg/ml

View all NQO-2 Antibodies »

Product Specifications

Immunogen

Recombinant human NQO-2 (1-231aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for NQO-2 Antibody (1E3) - BSA Free

Western Blot: NQO-2 Antibody (1E3)BSA Free [NBP1-74033]

Western Blot: NQO-2 Antibody (1E3)BSA Free [NBP1-74033]

Western Blot: NQO-2 Antibody (1E3) [NBP1-74033] - Mouse liver lysates (35ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NQO2 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Applications for NQO-2 Antibody (1E3) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NQO-2

Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates.NQO2 is inhibited by flavones such as quercetin. Also benzo(a)pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates.The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.

Long Name

NAD(P)H Dehydrogenase, Quinone 2

Alternate Names

DHQV, DIA6, NMOR2, NQO2, QR2, Quinone Reductase 2

Gene Symbol

NQO2

UniProt

AAH06096 (Human)

Additional NQO-2 Products

Product Documents for NQO-2 Antibody (1E3) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NQO-2 Antibody (1E3) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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