NRSF Antibody (SR1230)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21822

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21822-100ul
NBP3-21822-50ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1230

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all REST/NRSF Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human NRSF (Uniprot #: Q13127)

Specificity

Detects endogenous levels of total NRSF

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NRSF Antibody (SR1230)

Western Blot: NRSF Antibody (SR1230) [NBP3-21822] -

Western Blot: NRSF Antibody (SR1230) [NBP3-21822] - Western blot analysis using NBP3-21822 in HeLa cell lysate.

Applications for NRSF Antibody (SR1230)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: REST/NRSF

REST, which is short for RE1-silencing transcription factor, locks down neuronal genes in other cells by grabbing onto the DNA and cementing in other molecules, an arrangement that stays intact as non-neuronal cells differentiate into liver, muscle, and other tissues. REST uses a different temporary off mechanism to direct neuronal development. REST is a tumor suppressor gene in epithelial cells and has been found to be mutated in 33 percent of colorectal tumors and cell lines studied. Rest could eventually serve as a marker for diagnosing colorectal and other types of cancer.

Long Name

RE1-Silencing Transcription Factor

Alternate Names

NRSF, XBR

Gene Symbol

REST

Additional REST/NRSF Products

Product Documents for NRSF Antibody (SR1230)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NRSF Antibody (SR1230)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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