Nse2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00286053-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Nse2 Antibodies »

Product Specifications

Immunogen

C8orf36 (NP_775956, 1 a.a. - 247 a.a.) full-length human protein. MPGRSSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRHRHSE

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for Nse2 Antibody

Western Blot: Nse2 Antibody [H00286053-B01P]

Western Blot: Nse2 Antibody [H00286053-B01P]

Western Blot: Nse2 Antibody [H00286053-B01P] - Analysis of NSMCE2 expression in transfected 293T cell line by NSMCE2 polyclonal antibody. Lane 1: C8orf36 transfected lysate(27.17 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Nse2 Antibody [H00286053-B01P]

Immunocytochemistry/ Immunofluorescence: Nse2 Antibody [H00286053-B01P]

Immunocytochemistry/Immunofluorescence: Nse2 Antibody [H00286053-B01P] - Analysis of purified antibody to NSMCE2 on HeLa cell. (antibody concentration 10 ug/ml)

Applications for Nse2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is useful for Western Blot, Immunofluorescence
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Nse2

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair

Alternate Names

C8orf36, E3 SUMO-protein ligase NSE2, EC 6.3.2, EC 6.3.2.-, FLJ32440, hMMS21, methyl methanesulfonate sensitivity gene 21, MMS21 homolog, MMS21chromosome 8 open reading frame 36, Non-SMC element 2 homolog, non-SMC element 2 homolog (MMS21, S. cerevisiae), non-SMC element 2, MMS21 homolog (S. cerevisiae), Non-structural maintenance of chromosomes element 2 homolog, NSE2

Gene Symbol

NSMCE2

UniProt

NP_775956 (Human)

Additional Nse2 Products

Product Documents for Nse2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Nse2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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