NTB-A/SLAMF6/CD352 Antibody (005) [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90027V

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 005

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NTB-A/SLAMF6 Antibodies »

Product Summary for NTB-A/SLAMF6/CD352 Antibody (005) [DyLight 405]

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human NTB-A/SLAMF6/CD352 (Uniprot#: Q96DU3-1; Met1-Met226).

Specificity

No cross-reactivity in ELISA with: Human SLAMF7

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for NTB-A/SLAMF6/CD352 Antibody (005) [DyLight 405]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: NTB-A/SLAMF6

NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.

Long Name

NK-T-B Antigen/SLAM Family Member 6

Alternate Names

CD352, NTBA, SLAMF6

Gene Symbol

SLAMF6

Additional NTB-A/SLAMF6 Products

Product Documents for NTB-A/SLAMF6/CD352 Antibody (005) [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NTB-A/SLAMF6/CD352 Antibody (005) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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