NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43344

Novus Biologicals, part of Bio-Techne
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NBP1-43344-0.025mg
NBP1-43344-0.1mg
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Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 13G3-19D

Concentration

0.5 mg/ml

View all NTB-A/SLAMF6 Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody was Ly108.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

Flow Cytometry: NTB-A/SLAMF6/CD352 Antibody (13G3-19D) [NBP1-43344]

Flow Cytometry: NTB-A/SLAMF6/CD352 Antibody (13G3-19D) [NBP1-43344]

Flow Cytometry: NTB-A/SLAMF6/CD352 Antibody (13G3-19D) [NBP1-43344] - Staining of BALB/c splenocytes with 0.25 ug of Mouse IgG2a kappa Isotype Control Purified (open histogram) or 0.25 ug of Anti-Mouse Ly-108 Purified (filled histogram) followed by Anti-Mouse IgG2a Biotin and Streptavidin PE. Cells in the lymphocyte gate were used for analysis.

Applications for NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
This 13G3-19D antibody has been tested by flow cytometric analysis of mouse splenocytes and thymocytes. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

TBS (pH 8.0)

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: NTB-A/SLAMF6

The 13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions. Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.

Long Name

NK-T-B Antigen/SLAM Family Member 6

Alternate Names

CD352, NTBA, SLAMF6

Gene Symbol

SLAMF6

Additional NTB-A/SLAMF6 Products

Product Documents for NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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