NTB-A/SLAMF6/CD352 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49002

Novus Biologicals, part of Bio-Techne
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NBP2-49002
NBP2-49002-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NTB-A/SLAMF6 Antibodies »

Product Summary for NTB-A/SLAMF6/CD352 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LPLEFPAGEKVNFITWLFNETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NTB-A/SLAMF6/CD352 Antibody

Immunohistochemistry-Paraffin: NTB-A/SLAMF6/CD352 Antibody [NBP2-49002]

Immunohistochemistry-Paraffin: NTB-A/SLAMF6/CD352 Antibody [NBP2-49002]

Immunohistochemistry-Paraffin: NTB-A/SLAMF6/CD352 Antibody [NBP2-49002] - Staining of human tonsil shows moderate positivity in germinal center and non-germinal center cells.

Applications for NTB-A/SLAMF6/CD352 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NTB-A/SLAMF6

NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.

Long Name

NK-T-B Antigen/SLAM Family Member 6

Alternate Names

CD352, NTBA, SLAMF6

Gene Symbol

SLAMF6

Additional NTB-A/SLAMF6 Products

Product Documents for NTB-A/SLAMF6/CD352 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NTB-A/SLAMF6/CD352 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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