NTS2/NTSR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14430

Novus Biologicals, part of Bio-Techne
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NBP3-14430
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (95%), Canine (95%), Monkey (95%), Mouse (90%), Primate (90%). Backed by our 100% Guarantee.

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all NTS2/NTSR2 Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from internal region of human NTS2/NTSR2.

Epitope

Internal

Reactivity Notes

Expected reactivity based on percent sequence identity: Hamster (85%), Rabbit (80%)

Specificity

Human NTS2/NTSR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for NTS2/NTSR2 Antibody

Immunohistochemistry-Paraffin: NTS2/NTSR2 Antibody [NBP3-14430]

Immunohistochemistry-Paraffin: NTS2/NTSR2 Antibody [NBP3-14430]

Immunohistochemistry-Paraffin: NTS2/NTSR2 Antibody [NBP3-14430] - NTS2/NTSR2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Applications for NTS2/NTSR2 Antibody

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 10 ug/ml..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: NTS2/NTSR2

Official Gene Symbol: NTSR2 Gen Bank Accession Number: NP_036476 Gene ID: 23620 (Human) Gene Map Locus: 2p25.1 (Human) NTR2 is a member of GPCR family. It contains a short N-terminal sequence, 7 transmembrane domains and a short cytoplasmic tail. It is a low affinity levocabastine-sensitive receptor for Neurotensin. Activation of NT2R by non-peptide agonists suggests that the receptor can couple to phospholipase C, phospholipase A2 and MAPK. Unlike NTR1, NTR2 is insensitive to GTP and has low sensitivity of sodium ions. Northern Blot analysis detected its expression in adult brain regions including the olfactory system, cerebral and crebellar cortices, hippocampus and hypothalamic nuclei. Its expression has also been found in low levels in kidney, uterus, heart and lung.

Long Name

Neurotensin Receptor 2

Alternate Names

NTSR2

Gene Symbol

NTSR2

Additional NTS2/NTSR2 Products

Product Documents for NTS2/NTSR2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NTS2/NTSR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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