Nucleoporin 107 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76927

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Nucleoporin 107 Antibodies »

Product Summary for Nucleoporin 107 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human NUP107. The immunogen is located within amino acids 820 - 870 of NUP107. Amino Acid Squence: DVREDAKEDHERTHQ

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Nucleoporin 107 Antibody - BSA Free

Western Blot: Nucleoporin 107 AntibodyBSA Free [NBP1-76927]

Western Blot: Nucleoporin 107 AntibodyBSA Free [NBP1-76927]

Western Blot: Nucleoporin 107 Antibody [NBP1-76927] - A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody - BSA Free [NBP1-76927]

Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody - BSA Free [NBP1-76927]

Immunocytochemistry/Immunofluorescence: Nucleoporin 107 Antibody [NBP1-76927] - Immunofluorescence of NUP107 in A549 cells with NUP107 antibody at 10 ug/mL.
Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody - BSA Free [NBP1-76927]

Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody - BSA Free [NBP1-76927]

Immunocytochemistry/Immunofluorescence: Nucleoporin 107 Antibody [NBP1-76927] - A549 cells with Nucleoporin 107 antibody at 2.5 ug/ml.

Applications for Nucleoporin 107 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2.5-10 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nucleoporin 107

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

Alternate Names

nuclear pore complex protein Nup107, nucleoporin 107kDa, NUP84Nucleoporin Nup107,107 kDa nucleoporin

Gene Symbol

NUP107

UniProt

P57740 (Human)

Additional Nucleoporin 107 Products

Product Documents for Nucleoporin 107 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Nucleoporin 107 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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