Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rabbit (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Nudel Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Nudel. The immunogen is located within the first 50 amino acids of Nudel. Amino Acid Squence: MDGEDIPDFSSLKEE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Nudel Antibody - BSA Free

Western Blot: Nudel AntibodyBSA Free [NBP1-76677]

Western Blot: Nudel AntibodyBSA Free [NBP1-76677]

Western Blot: Nudel Antibody [NBP1-76677] - Jurkat whole cell lysate with Nudel antibody at (A) 0.5, (B) 1, or (C) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: Nudel Antibody - BSA Free [NBP1-76677]

Immunocytochemistry/ Immunofluorescence: Nudel Antibody - BSA Free [NBP1-76677]

Immunocytochemistry/Immunofluorescence: Nudel Antibody [NBP1-76677] - Immunofluorescence of Nudel in Jurkat cells with Nudel antibody at 10 ug/mL.
Immunocytochemistry/ Immunofluorescence: Nudel Antibody - BSA Free [NBP1-76677]

Immunocytochemistry/ Immunofluorescence: Nudel Antibody - BSA Free [NBP1-76677]

Immunocytochemistry/Immunofluorescence: Nudel Antibody [NBP1-76677] - Jurkat cells with Nudel antibody at 2 ug/ml.
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Applications for Nudel Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nudel

Nudel was initially discovered as a protein homologous to Aspergillus NUDE and that associated with Lis1 and polyprotein complex cytoplasmic dynein, both of which have been linked to neuronal development and migration. It was later shown to be a substrate of cdk5, a kinase known to be critical during neuronal migration; phosphorylation of Nudel by cdk5 affects its localization in neurons and affects neuritic morphology. It is thought that together with Lis1, Nudel regulates cytoplasmic dynein, a large polyprotein complex, in neuronal migration and mitosis through direct interactions. Similar interactions are thought to also play a role in membrane traffic in other cells as disruption of Nudel expression through RNA interference perturbed normal endomembrane flux and resulted in the fragmentation of the Golgi apparatus.

Alternate Names

DKFZp451M0318, EOPA, MITAP1mitosin-associated protein MITAP1, Mitosin-associated protein 1, nuclear distribution protein nudE-like 1, nudE nuclear distribution gene E homolog (A. nidulans)-like 1, nudE nuclear distribution gene E homolog like 1, nudE nuclear distribution gene E homolog like 1 (A. nidulans), NUDELendooligopeptidase A, NUDE-like protein, Protein Nudel

Gene Symbol

NDEL1

UniProt

AAF97497 (Human)

Additional Nudel Products

Product Documents for Nudel Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Nudel Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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