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Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25582

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-25582

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL1852

Format

Azide and BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

Immunogen

Recombinant fragment of human Nurr1/NGFI-B beta/NR4A2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free [NBP3-25582] -

Immunocytochemistry/Immunofluorescence: Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free [NBP3-25582] - Nurr1 antibody [HL1852] detects Nurr1 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Nurr1 stained by Nurr1 antibody [HL1852] (NBP3-25582) diluted at 1:500. Blue: Fluoroshield with DAPI .

Applications for Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nurr1/NGFI-B beta/NR4A2

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

Long Name

Nur-related Factor 1/Nerve Growth Factor Induced B beta/Nuclear Receptor Subfamily 4, Group A, 2

Alternate Names

NGFI-B beta, NOT, NR4A2, TINUR

Gene Symbol

NR4A2

Additional Nurr1/NGFI-B beta/NR4A2 Products

Product Documents for Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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