OATP1B1/OATP2 Antibody (ESL)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-74481

Novus Biologicals, part of Bio-Techne
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NB100-74481
NB100-74481-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human, Canine (Negative), Mouse (Negative), Rat (Negative)

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgM Clone # ESL

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all OATP1B1/OATP2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.

Localization

Cell Membrane; multi pass membrane protein

Specificity

OATP2 (ESL)

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Applications for OATP1B1/OATP2 Antibody (ESL)

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunofluorescence

1:100

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Frozen

1:10 - 1:500

Immunohistochemistry-Paraffin

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500

Western Blot

1:1000
Application Notes
Flow usage was reported in scientific literature (PMID: 25916617). IF: Staining of OATP2 in human liver samples results in a pattern consistent with plasma membrane staining.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Tissue culture supernatant

Preservative

0.09% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: OATP1B1/OATP2

The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Long Name

Sodium-independent Organic Anion-transporting Polypeptide 2

Alternate Names

HBLRR, LST1, OATP2, OATPC, SLC01B1, SLC21A6, SLCO1B1, SO1B1

Entrez Gene IDs

10599 (Human)

Gene Symbol

SLCO1B1

Additional OATP1B1/OATP2 Products

Product Documents for OATP1B1/OATP2 Antibody (ESL)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for OATP1B1/OATP2 Antibody (ESL)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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