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OBFC2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82718

Novus Biologicals, part of Bio-Techne
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NBP1-82718
NBP1-82718-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GGGPHPPHTPSHPPSTRITRSQPNHTPAGP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for OBFC2B Antibody

Immunocytochemistry/ Immunofluorescence: OBFC2B Antibody [NBP1-82718]

Immunocytochemistry/ Immunofluorescence: OBFC2B Antibody [NBP1-82718]

Immunocytochemistry/Immunofluorescence: OBFC2B Antibody [NBP1-82718] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: OBFC2B Antibody [NBP1-82718]

Immunohistochemistry-Paraffin: OBFC2B Antibody [NBP1-82718]

Immunohistochemistry-Paraffin: OBFC2B Antibody [NBP1-82718] - Staining of human pancreas shows strong nuclear positivity in exocrine glandular cells.
Immunohistochemistry-Paraffin: OBFC2B Antibody [NBP1-82718]

Immunohistochemistry-Paraffin: OBFC2B Antibody [NBP1-82718]

Immunohistochemistry-Paraffin: OBFC2B Antibody [NBP1-82718] - Staining of human cerebral cortex shows moderate nuclear positivity in neurons.

Applications for OBFC2B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OBFC2B

Single-stranded DNA -binding protein (SSB1) is phosphorylated by ATM in response to DNA damage. SSB1 is required for checkpoint activation and is critical for genomic stability.

Alternate Names

LP3587, MGC2731, oligonucleotide/oligosaccharide-binding fold containing 2B, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, Single-stranded DNA-binding protein 1, SOSS complex subunit B1, SOSS-B1, SSB1hSSB1

Entrez Gene IDs

79035 (Human)

Gene Symbol

NABP2

UniProt

Additional OBFC2B Products

Product Documents for OBFC2B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for OBFC2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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