OCRL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19621

Novus Biologicals, part of Bio-Techne
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NBP2-19621
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all OCRL Antibodies »

Product Summary for OCRL Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human OCRL. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rhesus Macaque, Mouse, Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

104 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for OCRL Antibody

Western Blot: OCRL Antibody [NBP2-19621]

Western Blot: OCRL Antibody [NBP2-19621]

Western Blot: OCRL Antibody [NBP2-19621] - Sample (30 ug of whole cell lysate) A: 293T B: A431 5% SDS PAGE gel, diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: OCRL Antibody [NBP2-19621]

Immunocytochemistry/ Immunofluorescence: OCRL Antibody [NBP2-19621]

Immunocytochemistry/Immunofluorescence: OCRL Antibody [NBP2-19621] - A431 cells were fixed in ice-cold MeOH for 5 min. Green: OCRL protein stained by OCRL antibody diluted at 1:500. Blue: Hoechst 33342 staining.
Immunohistochemistry-Paraffin: OCRL Antibody [NBP2-19621]

Immunohistochemistry-Paraffin: OCRL Antibody [NBP2-19621]

Immunohistochemistry-Paraffin: OCRL Antibody [NBP2-19621] - Human breast cancer, using OCRL antibody at 1:250 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for OCRL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris-Glycine (pH7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: OCRL

This gene encodes a phosphatase enzyme that is involved in actin polymerization and is found in the trans-Golgi network. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. [provided by RefSeq]

Alternate Names

EC 3.1.3.36, INPP5F, LOCR, Lowe oculocerebrorenal syndrome protein, NPHL2, OCRL1inositol polyphosphate 5-phosphatase OCRL-1, oculocerebrorenal syndrome of Lowe, phosphatidylinositol polyphosphate 5-phosphatase

Gene Symbol

OCRL

UniProt

Q01968 (Human)

Additional OCRL Products

Product Documents for OCRL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for OCRL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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