ORP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92233

Novus Biologicals, part of Bio-Techne
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NBP1-92233
NBP1-92233-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ORP1 Antibodies »

Product Summary for ORP1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VPKNSLQQSREDWLEAIEEHSAYSTHYCSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLPSFLQKVEVVSEA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%) Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ORP1 Antibody

Immunohistochemistry-Paraffin: ORP1 Antibody [NBP1-92233]

Immunohistochemistry-Paraffin: ORP1 Antibody [NBP1-92233]

Immunohistochemistry-Paraffin: ORP1 Antibody [NBP1-92233] - Staining of human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells.

Applications for ORP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ORP1

Oxysterols are oxygenated derivatives of cholesterol that have a number of biological effects and play a key role in the maintenance of the body cholesterol balance. ORP1 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that are believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase.

Alternate Names

FLJ10217, ORP1oxysterol-binding protein-related protein 1, ORP-1oxysterol-binding protein-related protein 1 variant 1, OSBP8, OSBPL1, OSBPL1B, OSBP-related protein 1, oxysterol binding protein-like 1A, oxysterol binding protein-like 1B, oxysterol-binding protein-related protein 1 variant 2

Gene Symbol

OSBPL1A

Additional ORP1 Products

Product Documents for ORP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ORP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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