OS9 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84803
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Summary for OS9 Antibody
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PLSCSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKML
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for OS9 Antibody
Immunohistochemistry-Paraffin: OS9 Antibody [NBP1-84803]
Immunohistochemistry-Paraffin: OS9 Antibody [NBP1-84803] - Staining of human placenta shows cytoplasmic positivity in trophoblastic cells.Applications for OS9 Antibody
Application
Recommended Usage
Immunohistochemistry
1:200 - 1:500
Immunohistochemistry-Paraffin
1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: OS9
Functionally, OS9 binds to HIF-1, a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. It may also bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. One such possible target includes TRPV4.
Alternate Names
Amplified in osteosarcoma 9, endoplasmic reticulum lectin 2, ERLEC2, erlectin 2, OS-9, osteosarcoma amplified 9, endoplasmic reticulum associated protein, osteosarcoma amplified 9, endoplasmic reticulum lectin, protein OS-9
Gene Symbol
OS9
Additional OS9 Products
Product Documents for OS9 Antibody
Product Specific Notices for OS9 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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