OS9 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97279
![Immunocytochemistry/ Immunofluorescence: OS9 Antibody [NBP2-97279]](https://resources.bio-techne.com/images/products/OS9-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-97279-img0001.jpg "Immunocytochemistry/ Immunofluorescence: OS9 Antibody [NBP2-97279]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for OS9 Antibody
Immunogen
Produced in rabbits immunized with E. coli-derived Human OS9 fragment.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Description
This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Scientific Data Images for OS9 Antibody
Immunocytochemistry/ Immunofluorescence: OS9 Antibody [NBP2-97279]
Immunocytochemistry/Immunofluorescence: OS9 Antibody [NBP2-97279] - Immunofluorescence staining of OS9 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human OS9 polyclonal antibody (dilution ratio 1:200) at 4C overnight. Then cells were stained with the Alexa Fluor(R)488-conjugated Goat Anti-rabbit IgG Secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.![Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279]](https://resources.bio-techne.com/images/products/OS9-Antibody-Immunohistochemistry-Paraffin-NBP2-97279-img0003.jpg "Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279]")
Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279]
Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279] - Staining of human OS9 in human pancreas with rabbit polyclonal antibody at 1:100 dilution.![Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279]](https://resources.bio-techne.com/images/products/OS9-Antibody-Immunohistochemistry-Paraffin-NBP2-97279-img0002.jpg "Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279]")
Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279]
Immunohistochemistry-Paraffin: OS9 Antibody [NBP2-97279] - Staining of human OS9 in human placenta with rabbit polyclonal antibody at 1:100 dilution.Applications for OS9 Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
1:100-1:500
Immunohistochemistry-Paraffin
1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen and protein A Affinity-purified
Formulation
PBS
Preservative
0.03% Proclin 300
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: OS9
Functionally, OS9 binds to HIF-1, a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. It may also bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. One such possible target includes TRPV4.
Alternate Names
Amplified in osteosarcoma 9, endoplasmic reticulum lectin 2, ERLEC2, erlectin 2, OS-9, osteosarcoma amplified 9, endoplasmic reticulum associated protein, osteosarcoma amplified 9, endoplasmic reticulum lectin, protein OS-9
Gene Symbol
OS9
Additional OS9 Products
Product Specific Notices for OS9 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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