OSBPL2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1332

Novus Biologicals, part of Bio-Techne
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NB100-1332
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all OSBPL2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence YFERNFSDCPDIY corresponding to C-Terminus according to NP_055650.1, NP_653081.1.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 22241858).

Localization

Golgi Apparatus

Specificity

This antibody is expected to recognise both reported isoforms (represented by NP_055650.1 and NP_653081.1)

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for OSBPL2 Antibody

Western Blot: OSBPL2 Antibody [NB100-1332]

Western Blot: OSBPL2 Antibody [NB100-1332]

Western Blot: OSBPL2 Antibody [NB100-1332] - NB100-1332 staining (1.5 ug/ml) of human heart lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected using chemiluminescence.

Applications for OSBPL2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

1 - 2 ug/ml
Application Notes
WB: Approx. 55-60 kDa band observed in human heart lysates (predicted MW of 54 and 55 kDa band according to NP_055650.1 and NP_653081.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: OSBPL2

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Alternate Names

KIAA0772FLJ20223, ORP-2MGC4307, ORP2MGC8342, OSBP-related protein 2, oxysterol binding protein-like 2, oxysterol-binding protein-like 2, oxysterol-binding protein-related protein 2

Entrez Gene IDs

9885 (Human); 228983 (Mouse)

Gene Symbol

OSBPL2

UniProt

NP_055650 (Human)

Additional OSBPL2 Products

Product Documents for OSBPL2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for OSBPL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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