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OSTM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19641

Novus Biologicals, part of Bio-Techne
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NBP2-19641

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (90%), Monkey (99%), Rabbit (92%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for OSTM1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human OSTM1. The exact sequence is proprietary.

Reactivity Notes

Mouse (81%), Rat (83%).

Localization

Membrane; Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for OSTM1 Antibody

Western Blot: OSTM1 Antibody [NBP2-19641]

Western Blot: OSTM1 Antibody [NBP2-19641]

Western Blot: OSTM1 Antibody [NBP2-19641] - Sample (30 ug of whole cell lysate) A: Raji B: HL-60 10% SDS PAGE gel, diluted at 1:1000.

Applications for OSTM1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: OSTM1

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq]

Alternate Names

GIPN, GLGAIP-interacting protein N terminus, grey-lethal osteopetrosis, HSPC019, OPTB5, osteopetrosis associated transmembrane protein 1, osteopetrosis-associated transmembrane protein 1

Gene Symbol

OSTM1

UniProt

Additional OSTM1 Products

Product Documents for OSTM1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for OSTM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.