Oval Cell Marker Antibody (MIC1-1C3) [PE/Cy5.5]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-18961PECY55

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

PE/Cy5.5 (Excitation = 488 nm, Emission = 695 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # MIC1-1C3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Oval Cell Marker Antibodies »

Product Summary for Oval Cell Marker Antibody (MIC1-1C3) [PE/Cy5.5]

Immunogen

Nonparenchymal cells from DDC-treated mice

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 30236451).

Localization

Cell surface

Specificity

Specific for hepatic proliferating duct cells.

Marker

Hepatic periductal cell Marker

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Oval Cell Marker Antibody (MIC1-1C3) [PE/Cy5.5]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Oval Cell Marker

Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.

Additional Oval Cell Marker Products

Product Documents for Oval Cell Marker Antibody (MIC1-1C3) [PE/Cy5.5]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Oval Cell Marker Antibody (MIC1-1C3) [PE/Cy5.5]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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