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Oval Cell Marker Antibody (OC2-2F3) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-18964G

Novus Biologicals, part of Bio-Techne
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NBP1-18964G
Conjugate
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Rat IgG1 Clone # OC2-2F3

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Summary for Oval Cell Marker Antibody (OC2-2F3) [DyLight 488]

Immunogen

Nonparenchymal cells from DDC-treated mice

Localization

Cell surface

Specificity

Specific for proliferating hepatic duct cells.

Marker

Hepatic periductal cell Marker

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Description

This product is provided as conjugated tissue culture supernatant. Due to the crude preparation of the antibody material, excess dye may remain in the final product. We highly recommend taking necessary precautions, such as adding additional wash steps and running proper controls.

Applications for Oval Cell Marker Antibody (OC2-2F3) [DyLight 488]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Tissue culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Oval Cell Marker

Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.

Additional Oval Cell Marker Products

Product Documents for Oval Cell Marker Antibody (OC2-2F3) [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Oval Cell Marker Antibody (OC2-2F3) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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