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OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-75913

Novus Biologicals, part of Bio-Techne
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NBP2-75913-0.2mg
NBP2-75913SS

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Human IgG1 kappa Clone # R4930 (Oxelumab)

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Oxelumab binds to human OX40L, the ligand of OX40, stimulatory receptor that is expressed on activated T cells, natural killer (NK) cells and natural killer T (NKT) cells.

Specificity

Binds to human OX40L.

Clonality

Monoclonal

Host

Human

Isotype

IgG1 kappa

Scientific Data Images for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free

Flow Cytometry: OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free [NBP2-75913]

Flow Cytometry: OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free [NBP2-75913]

Flow Cytometry: OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [NBP2-75913] - Human peripheral blood leukocytes were fixed using 2% PFA, permeabilised using 0.5% Triton and stained with unimmunized rabbit IgG antibody (MOPC-21; isotype control, black line) or the rabbit IgG-chimeric version of R4930 (blue line). After washing, bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody and cells analyzed using a FACSCanto flow-cytometer.

Applications for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: OX40 Ligand/TNFSF4

CD252 is a 35 kD member of the TNF superfamily also known as OX40L and CD134L. The OX40 ligand is expressed on activated B cells and antigen presenting cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to increase proliferation and IL-2 production, and to enhance proliferation and immunoglobulin secretion in activated B cells. The RM134L antibody can inhibit OX40/OX40 ligand interactions and block the costimulatory activity of OX40L.

Alternate Names

CD252, gp34, TNFSF4, biosimilar antibody, biosimilars

Gene Symbol

TNFSF4

Additional OX40 Ligand/TNFSF4 Products

Product Documents for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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