p114RhoGEF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92238

Novus Biologicals, part of Bio-Techne
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NBP1-92238
NBP1-92238-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all p114RhoGEF Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPAGPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESI

Reactivity Notes

Reactivity reported in scientific literature (PMID: 25646088)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for p114RhoGEF Antibody

Immunocytochemistry/ Immunofluorescence: p114RhoGEF Antibody [NBP1-92238]

Immunocytochemistry/ Immunofluorescence: p114RhoGEF Antibody [NBP1-92238]

Immunocytochemistry/Immunofluorescence: p114RhoGEF Antibody [NBP1-92238] - Staining of human cell line A-431 shows localization to plasma membrane & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: p114RhoGEF Antibody [NBP1-92238]

Immunohistochemistry-Paraffin: p114RhoGEF Antibody [NBP1-92238]

Immunohistochemistry-Paraffin: p114RhoGEF Antibody [NBP1-92238] - Staining of human small intestine shows strong cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: p114RhoGEF Antibody [NBP1-92238]

Immunohistochemistry-Paraffin: p114RhoGEF Antibody [NBP1-92238]

Immunohistochemistry-Paraffin: p114RhoGEF Antibody [NBP1-92238] - Staining of human liver shows moderate cytoplasmic positivity in Kupffer cells.
View 2 more images

Applications for p114RhoGEF Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p114RhoGEF

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Alternate Names

114 kDa Rho-specific guanine nucleotide exchange factor, EC 3.4.24, EC 3.6.1, KIAA0521rho guanine nucleotide exchange factor 18, MGC15913, p114RhoGEF, P114-RhoGEF, P114-RHO-GEF, Rho/Rac guanine nucleotide exchange factor (GEF) 18, Rho/Rac guanine nucleotide exchange factor 18, Rho-specific guanine nucleotide exchange factor p114, SA-RhoGEF, Septin-associated RhoGEF

Gene Symbol

ARHGEF18

Additional p114RhoGEF Products

Product Documents for p114RhoGEF Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for p114RhoGEF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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