p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3216

Novus Biologicals, part of Bio-Techne
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NB120-3216
NB120-3216-100ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 18P118 (DCS-118)

Concentration

0.4 mg/ml

View all p18INK4c/CDKN2C Antibodies »

Product Specifications

Immunogen

Purified recombinant p18INK4c protein

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Localization

Nuclear. Cytoplasmic.

Specificity

p18 (18P118 (same as DCS-118))

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

Western Blot: p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) [NB120-3216]

Western Blot: p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) [NB120-3216]

Western Blot: p18INK4c/CDKN2C Antibody (18P118 (same as DCS-118)) [NB120-3216] - Analysis of HeLa Cells.
Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) [NB120-3216]

Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) [NB120-3216]

Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody (18P118 (same as DCS-118)) [NB120-3216] - Human tonsil stained with p18 (NB120-3216) using peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.
Immunoprecipitation: p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) [NB120-3216]

Immunoprecipitation: p18INK4c/CDKN2C Antibody (18P118 (DCS-118)) [NB120-3216]

Immunoprecipitation: p18INK4c/CDKN2C Antibody (18P118 (same as DCS-118)) [NB120-3216] - Analysis of native IP.

Applications for p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

Application
Recommended Usage

Immunofluorescence

1:10 - 1:500

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

1:50

Immunoprecipitation

1 - 2 ug/ml

Western Blot

1 - 2 ug/ml
Application Notes
WB: Detects an approx. 18 kDa, which corresponds to the predicted molecular weight of p18 / INK4c.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4) and 0.2% BSA

Preservative

0.09% Sodium Azide

Concentration

0.4 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: p18INK4c/CDKN2C

p18 INK4c is a specific inhibitor of cdk4 / cdk6 (interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels found in skeletal muscle. Also found in pancreas and heart.

Long Name

p18 Cyclin Dependent Kinase 4 Inhibitor 2C

Alternate Names

CDKN2C, p18-INK6

Entrez Gene IDs

1031 (Human); 12580 (Mouse)

Gene Symbol

CDKN2C

UniProt

P42773 (Human)

Additional p18INK4c/CDKN2C Products

Product Documents for p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for p18INK4c/CDKN2C Antibody (18P118 (DCS-118))

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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