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p18INK4c/CDKN2C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87687

Novus Biologicals, part of Bio-Techne
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NBP1-87687
NBP1-87687-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for p18INK4c/CDKN2C Antibody

Western Blot: p18INK4c/CDKN2C Antibody [NBP1-87687]

Western Blot: p18INK4c/CDKN2C Antibody [NBP1-87687]

Western Blot: p18INK4c/CDKN2C Antibody [NBP1-87687] - Analysis in control (vector only transfected HEK293T lysate) and CDKN2C over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody [NBP1-87687]

Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody [NBP1-87687]

Immunohistochemistry-Paraffin: p18INK4c/CDKN2C Antibody [NBP1-87687] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Applications for p18INK4c/CDKN2C Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p18INK4c/CDKN2C

p18 INK4c is a specific inhibitor of cdk4 / cdk6 (interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels found in skeletal muscle. p18 INK4c is also found in pancreas and heart.

Long Name

p18 Cyclin Dependent Kinase 4 Inhibitor 2C

Alternate Names

CDKN2C, p18-INK6

Gene Symbol

CDKN2C

Additional p18INK4c/CDKN2C Products

Product Documents for p18INK4c/CDKN2C Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p18INK4c/CDKN2C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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